Although some alternative therapies like botanical and herbal therapies have shown promise for relieving menopause symptoms such as hot flashes, more research is needed. Eighty-five percent of the women in the United States experience hot flashes of some kind as they approach menopause and for the first year or two after their periods stop. Between 20 and 50% of women continue to have them for many more years. As time goes on, the intensity decreases. In this review we focus on the evidence based herbal medicine in particular with herbs that have antidepressant effects.